08/2024:

Ines Rosignol successfully defended her PhD with Magna Cum Laude. Congratulations Ines, well done, we are very proud of you!!! 

08/2024:

Lab retreat to the Saxony Swiss.  On a beautiful sunny day we paddled 19km from Kurort Rathen back to Dresden. Including several breaks to swim in the Elbe or to have lunch or ice-cream, it took as 6 hours. What a great day!

06/2024: Open Day at DZNE Bonn  
We had a great time presenting our work at DZNE Open Day at the Venusberg-Campus in Bonn on June 16th 2024. Overall more than 3000 people stopped by. Thanks to everybody who joined us on this nice trip!

11/2023:

Natalia Rodríguez-Muela was awarded a research Grant from the German Research Foundation (DFG)!

Congratulations!!!

09/2023:

Natalia Rodríguez-Muela presented at German Stem Cell Network (GSCN), Ulm, Germany,  Title of her talk: “An isogenic human iPSC model unravels neurodevelopmental abnormalities in spinal muscular atrophy”

06/2023:

Joshua Thomas, Phd Student, gave a talk at EMBO: Cell biology of the nervous system conference, Crete, Greece; title of his talk: “SMN Protein Level as a Driver of Selective Motor Neuron Vulnerability”

Congratulations, Josh!

06/2023:

Natalia Rodríguez-Muela presented at the Wiley China “Best of CureSMA 2023” Webinar 

Congratulations for being selected to participate and present!

05/2023:

Our Review „Spinal Cord Organoids to Study Motor Neuron Development and Disease“ has been published in Life. Congratulations to all authors for this fantastic and very thorough review!

08/2022:

Felix Buchner, M.Sc. was awarded a grant from the FOSTER award funding program of TU Dresden.

Congratulations, Felix! 

03/2022:

Natalia Rodríguez-Muela presented at the Stem Cell Winter School: Stem Cells for Disease Modeling and Regeneration, Tübingen, Germany, title of her talk: “Spinal cord organoids to model and study motoneuron disease neuropathology” 

07/2020:

Natalia Rodríguez-Muela presented at the DIPP Vision Series Talk– Dresden International PhD program, title of the talk: “The mystery of selective neuronal vulnerability in neurodegenerative diseases” 

06/2019:

Natalia Rodríguez-Muela presented at MDA Clinical & Scientific Conference, Orlando, USA, title of the talk: “Involvement of selective autophagy in spinal muscular atrophy pathology” – MDA Clinical & Scientific Conference, Orlando, USA (2019)

03/2019:

Natalia Rodríguez-Muela presented at IMBA Mini-Symposium on Stem Cell Biology, Vienna, Austria , title of the talk: “Resistance versus vulnerability: unraveling the fate of neuronal subtypes in neuropathologies”

07/2024:

Our Paper has been published in Cell Reports Medicine. Using the first isogenic hiPSC SMA model and our advanced spinal cord organoid system we have discovered fate commitment defects of neuromesodermal progenitors during the early embryonic development in Spinal Muscular Atrophy, long before motor neuron loss! Some more info and press releases can be found here:

DZNE
Informationsdienst Wissenschaft
Genetic Engineering & Biotechnology News
Sciencedaily

04/2024:

Check our seminar on our latest advances in SMA research in the education platform for doctors VUMEDI. It can be found here!

11/2023:

Natalia Rodríguez-Muela presented at  „Syntophagy“, Magdeburg, Germany, title of her talk “Dysfunction of the lysosome-autophagy system renders motoneurons selectively vulnerable in spinal muscular atrophy” 

10/2023:

Natalia Rodríguez-Muela presented at EMBO/EMBL- Organoids: modelling organ development and disease in 3D culture, Heidelberg, Germany (Oct 2023). Title of her talk: “Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation” 

10/2023:

Natalia Rodríguez-Muela presented at EMBO/EMBL- Organoids: modelling organ development and disease in 3D culture, Heidelberg, Germany (Oct 2023). Title of her talk: “Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation” 

06/2023:

Joshua Thomas, Phd Student, received a travel award from the DIGS-BB (Dresden International Graduate School for Biomedicine).

Congratulations, Josh!

06/2023:

Natalia Rodríguez-Muela gave a talk at the Annual SMA Research & Clinical Care Meeting, Orlando, US, title of the talk: “Human spinal cord organoid models of spinal muscular atrophy exhibit early neurodevelopmental defects”

Congratulations!

03/2024:

Natalia Rodríguez-Muela gave a talk at SMA Europe, Ghent, Belgium, titled: “Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal
muscular atrophy initiation”.

Joshua Thomas, Phd Student,  presented his work during the official poster session, title of his poster: “SMN Protein Level as a Driver of Selective Motor Neuron Vulnerability”

Congrats to both of you! 

11/2022:

Natalia Rodríguez-Muela and Felix Buchner, M.Sc., have been awarded a grant from the German Society for Muscular Diseases (DGM). Title of the exciting and promising grant: „Optimization of modeling Spinal motor neuron diversity in Spinal Muscular Atrophy hiPSC-derived Spinal Cord Organoids for the study of selective neuronal vulnerability“

Congratulations!

05/2022:

Natalia Rodríguez-Muela presented at DZNE Metabolism MiniSymposium, Bonn, Germany , title of her talk: “Autophagy dysregulation in motor neuron diseases: A potential driver of selective neuronal vulnerability”

02/2021:

Natalia Rodríguez-Muela presented at the CURE-ND Neurotechnology Workshop-Innovative models of neurodegenerative diseases, title of her talk: “Human iPSC-derived models to decipher the mystery of selective neuronal vulnerability in motor neuron diseases”

09/2019:

Natalia Rodríguez-Muela presented at PROGENIE Meeting, Bordeaux, France, title of the talk: “Resistance versus vulnerability: unraveling the fate of neuronal subtypes in neuropathologies” 

04/2019:

Natalia Rodríguez-Muela presented at Annual AMPro Meeting – Helmholtz Association, title of the talk: “Resistance versus vulnerability: unraveling the fate of neuronal subtypes in neuropathologies”